1.Product Name: Lycoremine
2.CAS NO: 1953-04-4
3.Spec:98%Galantamine HBr(By HPLC)
4.M.F:C17H21NO3HBr

Galantamine Hydrobromide
[English Name] Galantamine Hydrobromide
[Molecular Formula] C17H21NO3*HBr
[Molecular Weight] 368.27
[CAS Number] 1953-04-04
[Plantresources] Galantamine is a kind of isoquinoline alkaloid that derivedfrom Leucojum aestivum, L. Radiata Herb., L. Aruea Herb. And L.Squamigeric Herb. Its bromide salt was frequently used in clinicalcases.
[Specification] 98%, 99%.
[Physical property] white-likepowder. Dissolve in water. Slightly dissolve in ethanol. Do not dissolvein chloroform and aether.

[Pharmacological effects]
Galanthamineis a kind of phenanthridine alkaloid discovered by former Soviet Unionscientists in 1950s. It is a reversible cholinesterase inhibitor whichcan inhibit acetylcholinesterase selectively. Galanthamine belongs tothe second generation of acetylcholinesterase inhibitors. In ourcountry, it was separated from domestic red indigo lycoris radiata andsafflower Lycoris radiata in 1960s, and was embodied in ChinesePharmacopoeia in 1977 with its bromide salt frequently used.

TheGalanthamine preparation on sale in the market is used to improve theoverall function of the patients suffering from Alzheimer diseaseclinically. This drug has dual mechanism, which can better stimulate andinhibit acetylcholinesterase, regulate intracephalic nicotine receptorposition, improve the recognition function of light, mild Alzheimerdisease patients significantly, and delay the process of functiondecrease of brain cells.

Galanthamine is a kind ofanticholinesterase drug, which can better improve the conduction betweennerve and muscle. It could be used myasthenia gravis, progressivemyodystrophy, Post Polio Syndrome, child brain paralysis, senseobstruction, cinesipathy and polyneuritis induced by nervous systemdiseases.

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